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Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
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Factor VIII-related antigen (VIII R:AG) in haemophilic patients and in carriers

E J Bowie, D N Fass

    Lancet (London, England)
    |November 17, 1979
    PubMed

    All of fourteen patients with severe classic haemophilia and twelve of fifteen obligate carriers had a pre-peak ("rocket") above the sample well when factor VIII-related antigen was examined by crossed immunoelectrophoresis. The pre-peak may be found in other conditions--including von Willebrand's disease--but if these conditions can be excluded, the pre-peak may be helpful in identification of carriers or haemophilia.

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