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Trigeminal trophic syndrome

C H Dicken1

  • 1Department of Dermatology, Mayo Clinic Rochester 55905, USA.

Mayo Clinic Proceedings
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

Trigeminal trophic syndrome causes persistent facial ulcers, particularly on the nose, following trigeminal nerve damage. Self-inflicted trauma is the suspected cause of these difficult-to-heal sores.

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Area of Science:

  • Neurology
  • Dermatology
  • Ophthalmology

Background:

  • Trigeminal trophic syndrome (TTS) is a rare condition characterized by neurotrophic facial ulcers.
  • These ulcers typically affect the ala nasi region within an anesthetic trigeminal nerve dermatome.
  • TTS often arises as a complication of trigeminal nerve ablation for trigeminal neuralgia.

Purpose of the Study:

  • To report on seven cases of trigeminal trophic syndrome.
  • To describe the clinical presentation and suspected etiology of TTS.
  • To highlight the persistent nature of these facial ulcers.

Main Methods:

  • Case series reporting on seven patients diagnosed with trigeminal trophic syndrome.
  • Review of patient histories detailing trigeminal nerve injury and ulcer onset.

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  • Clinical observation of ulcer characteristics and persistence.

    • Main Results:

    • Seven cases of trigeminal trophic syndrome were documented.
    • Ulcer onset ranged from weeks to several years post-trigeminal nerve injury, with a mean of 1-2 years.
    • Self-induced trauma is implicated as the primary mechanism for tissue destruction, leading to persistent ulcers.

    Conclusions:

    • Trigeminal trophic syndrome is a rare but significant complication of trigeminal nerve procedures.
    • The development of persistent, self-inflicted ulcers underscores the importance of recognizing this syndrome.
    • Early identification and management strategies are crucial for patients with trigeminal trophic syndrome.