Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extended lymph node dissection in gastrointestinal cancer

M Noguchi1, I Miyazaki

  • 1Operation Center, Kanazawa University Hospital, School of Medicine, Kanazawa University, Japan.

Journal of Surgical Oncology
|May 1, 1997
PubMed
Summary

Extended lymph node dissection shows potential survival benefits in gastrointestinal cancer, but evidence from high-quality trials is limited. Further randomized studies are needed to confirm its therapeutic value.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correlation between altered expression of retinoblastoma protein and clinical outcome in patients with gastric-cancer.

International journal of oncology·2011
Same author

Colonic prostaglandin-e2 in carcinogenesis in rats with N-methyl-n'-nitrosoguanidine.

International journal of oncology·2011
Same author

C-erbb-2, ras p21, and C-myc expression in breast-carcinoma - prognostic value and correlation with clinicopathological and biologic variables.

International journal of oncology·2011
Same author

Nm23 expression versus helix-pomatia lectin-binding in human breast-cancer metastases.

International journal of oncology·2011
Same author

Effects of linoleic acid and eicosanoid synthesis inhibitors on the growth and c-myc oncogene expression of human breast cancer cells.

International journal of oncology·2011
Same author

Correlation between overexpression of c-met gene and the progression of gastric cancer.

International journal of oncology·2011

Area of Science:

  • Oncology
  • Surgical Oncology

Background:

  • Extended lymph node dissection is a surgical technique used in gastrointestinal cancer treatment.
  • Its impact on patient survival remains a subject of ongoing research and debate.

Purpose of the Study:

  • To review the existing literature on the effect of extended lymph node dissection on survival in gastrointestinal cancer patients.
  • To evaluate the current evidence and identify gaps in knowledge regarding this surgical approach.

Main Methods:

  • A comprehensive literature review was conducted.
  • Analysis focused on retrospective, prospective nonrandomized, and prospective randomized trials concerning gastrointestinal cancers (esophageal, gastric, colorectal).

Main Results:

  • Nonrandomized studies often suggest improved survival with extended dissection in esophageal, gastric, and colorectal cancers.

Related Experiment Videos

  • However, prospective randomized trials in gastric cancer have not consistently shown a survival advantage.
  • High-quality randomized trials are scarce for esophageal and colorectal cancer.

    • Conclusions:

    • The definitive therapeutic value of extended lymph node dissection in gastrointestinal cancer is not yet established.
    • There is a critical need for well-designed, ethical, randomized prospective studies to clarify its survival benefits.