Related Experiment Video
Updated: Jun 29, 2026

2-Vessel Occlusion/Hypotension: A Rat Model of Global Brain Ischemia
Published on: June 22, 2013
[The distribution of cardiac output in waking rats with a decrease in body temperature to 2.3 degrees C through
Abstract:
Heart output distribution (HO) was characterised by incorporation of 15-micron 131-I [correction of 15- 131J]-albumin microspheres after cooling and altitude hypoxia in alert rats. There was no significant change in the HO distribution in experimental rats except a 1.5-fold increase of the skin HO portion and a 1.5-fold decrease of the bone marrow HO portion in hypothermic rats. The latter developed an increase in the blood flow in skeletal muscles and different skin parts as compared with the hypoxic rats.
Related Concept Videos
Decreased Body Temperature
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...

