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[New approaches to the eradication of enterobiasis in children]
Insights
This study identifies risk factors for enterobiasis in children, including developmental issues and early artificial feeding. Medamine treatment proved 100% effective, with probiotics aiding recovery and immunity.
Area of Science:
- Pediatrics
- Infectious Diseases
- Immunology
Background:
- Enterobiasis (pinworm infection) is common in children.
- Risk factors and the impact of enterobiasis on child development and immunity require further investigation.
Purpose of the Study:
- To identify risk factors for enterobiasis in children.
- To evaluate the efficacy of medamine, biologicals, and Normase in treating enterobiasis.
- To assess the impact of enterobiasis on child development and immunity.
Main Methods:
- Retrospective analysis of risk factors.
- Clinical evaluation of treatment efficacy.
- Assessment of immune markers (salivary lysozyme, blood alpha-interferon).
Main Results:
- Risk factors identified: abnormal antenatality, minor developmental anomalies, and early artificial feeding.
- Enterobiasis negatively impacts physical, nervous, and mental development, suppressing non-specific immunity.
- Medamine demonstrated 100% efficacy in a single course for enterobiasis treatment.
- Probiotics (bificol, bifidumbacterin) and Normase may enhance treatment and recovery.
Conclusions:
- Early identification of risk factors is crucial for enterobiasis prevention.
- Enterobiasis significantly compromises child development and immune function, affecting vaccine response.
- Medamine is a highly effective treatment, and probiotics can support recovery and immune restoration.
Abstract:
The paper outlines the results of studies dealt with the detection of risk factors and groups for enterobiasis, the efficiency of the treatment of children suffering from the disease with medamine, biologicals, and Normase. It is shown that risk factors may include an abnormal course of antenatality, minor developmental malformations (diastema, dystrophy, abnormalities of the eye, hand, foot, etc.), as well as early artificial feeding of babies (before they reach 3 months of life). Enterobiasis is found to have a negative influence on the physical, nervous, and mental development and suppression of non-specific immunity in children, which is suggested by the reduction in salivary lysozyme activity, which is lower than the normal level and on blood alpha-interferon production. There is strong evidence for the considerable immunosuppressive effects of enterobiasis on the formation of a postvaccinal immunity against measles. When given in a single course dose, medamine shows a 100% efficiency in the treatment of enterobiasis. Moreover, bificol, bifidumbacterin, and Normase may be useful to enhance the treatment efficiency and children's recovery from enterobiasis.