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Updated: Aug 13, 2026

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
Published on: June 18, 2020
[Doppler ultrasound of blood flow in the hepatic veins]
1Medisinsk avdeling, Regionsykehuset i Tromsø.
Insights
Doppler ultrasound easily studies hepatic vein blood flow. Its patterns reveal cardiac and liver conditions, aiding diagnosis and pathology grading in heart and liver disease.
Area of Science:
- Cardiology
- Hepatology
- Medical Imaging
Background:
- Hepatic vein blood flow is typically assessed using Doppler ultrasound.
- Normal flow patterns correlate with the cardiac cycle and right atrial pressure.
- Variations in flow can indicate cardiac or hepatic disease.
Purpose of the Study:
- To describe normal hepatic vein blood flow patterns.
- To explore how these patterns change in various cardiac and hepatic conditions.
- To evaluate the diagnostic utility of hepatic vein flow patterns.
Main Methods:
- Doppler ultrasound examination of hepatic veins.
- Analysis of blood flow patterns in relation to the cardiac cycle.
- Correlation of flow patterns with clinical diagnoses of cardiac and hepatic diseases.
Main Results:
- Normal hepatic vein flow exhibits specific variations linked to the cardiac cycle.
- Conditions like atrial fibrillation, tricuspid regurgitation, and cardiomyopathies alter flow patterns.
- Cirrhosis and portal hypertension reduce heart-synchronous velocity variations due to increased hepatic resistance.
Conclusions:
- Hepatic vein Doppler ultrasound is valuable for diagnosing and grading cardiac and hepatic pathologies.
- Altered flow patterns provide insights into conditions affecting the heart and liver.
- Reduced velocity variations in hepatic veins suggest increased intrahepatic resistance, as seen in cirrhosis.
Abstract:
The blood flow in the hepatic veins can normally be studied easily by Doppler ultrasound. The pattern of blood flow in normal individuals is described, and its relation to the cardiac cycle and changing pressure in the right atrium. The blood flow shows variations in healthy persons, and may change in cases of heart disease and hepatic disease. Conditions such as atrial fibrillation, tricuspid regurgitation, abnormal relaxation, restrictive cardiomyopathy, constrictive pericarditis and cardiac tamponade are reflected in the hepatic veins, and the pattern of blood flow may help in diagnosis, and in grading the pathology. In cirrhosis and portal hypertension the heart-synchronous variation in velocity is reduced. This is due to increased resistance to blood flow across the liver and the pressure gradient becoming larger than the variations in pressure in the right atrium.
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