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[The future of antiviral drugs]
L Moutouh1, V Calvez, J M Huraux
1Laboratoire de virologie, CERVI Hôpital Pitié-Salpêtnère, Paris.
Abstract:
Despite much recent progress, antiviral chemotherapy has still to meet some major challenges: residual cytotoxicity of much antiviral drugs; emergence of viral strains resisting to the most specific antiviral drugs; inability of the most active antiviral drugs to suppress latent viral infections. Several approaches using gene therapy (e.g. hybridons, ribozymes, or dominant negative mutants) might theoretically provide efficient solutions against viral latency.
Insights
Gene therapy offers potential solutions to overcome challenges in antiviral chemotherapy, including drug resistance and latent viral infections. Approaches like hybridons and ribozymes show promise for treating persistent viral diseases.
Area of Science:
- Virology
- Molecular Biology
- Gene Therapy