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Genes for interleukin-2 receptor beta chain, interleukin-1 beta, and schizophrenia: no evidence for the association
1Department of Psychiatry, Showa University School of Medicine, Tokyo, Japan.
American Journal of Medical Genetics
|May 31, 1997
Abstract:
We studied a CA repeat polymorphism of the interleukin-2 receptor beta chain (IL-2RB) gene and a C/-514/T variation of the interleukin-1 beta (IL-1B) gene in Japanese schizophrenia patients. Both a case-control association study (54 patients and 54 controls) and a linkage study using six multiplex families (the number of the affected > or =4 in each family) were employed. No evidence for the association or the linkage was obtained either for the IL-2RB or IL-1B gene.