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Related Experiment Videos

Some current aspects of environmental fluoride

J R Marier

    The Science of the Total Environment
    |November 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Human populations face increasing inorganic fluoride intake, particularly those with impaired kidney function or diabetes. This persistent bioaccumulator poses long-term health risks due to rising environmental fluoride levels.

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    Area of Science:

    • Environmental Health
    • Toxicology
    • Public Health

    Background:

    • Inorganic fluoride is a persistent bioaccumulator with increasing environmental release.
    • Growing concern exists regarding long-term fluoride exposure in susceptible human populations.
    • Specific at-risk groups include individuals with impaired kidney function and inadequate dietary intake.

    Purpose of the Study:

    • To conduct a Total Environment evaluation of current inorganic fluoride intake in human populations.
    • To identify and assess the risks associated with increasing fluoride exposure.
    • To highlight vulnerable sub-groups and contributing factors to fluoride intoxication.

    Main Methods:

    • Review of existing literature on inorganic fluoride intake and its environmental sources.

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  • Analysis of population sub-groups at higher risk due to physiological or dietary factors.
  • Examination of trends in daily fluoride intake through the food and beverage chain.

    • Main Results:

    • Evidence indicates an escalation in daily inorganic fluoride intake via the human food-and-beverage chain.
    • Individuals with impaired kidney function, including those with nephropathic diabetes, are at increased risk.
    • Inadequate dietary intake of calcium and/or Vitamin C exacerbates risks from chronic low-dose fluoride ingestion.
    • An increasing incidence of chronic fluoride intoxication in humans has been observed.

    Conclusions:

    • The escalating environmental fluoride levels and increasing dietary intake necessitate long-term health concern.
    • Vulnerable populations, such as those with kidney dysfunction or specific dietary deficiencies, require targeted monitoring and potential intervention.
    • Continued monitoring of fluoride intake and its health implications is crucial for public health protection.