Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Can (99m)technetium methylene diphosphonate bone scans objectively document costochondritis?

G Mendelson1, H Mendelson, S F Horowitz

  • 1Department of Medicine, Beth Israel Medical Center, New York, NY 10003, USA.

Chest
|June 1, 1997
PubMed
Summary

Bone imaging using 99mTc methylene diphosphonate is not a specific diagnostic tool for costochondritis in patients with chest pain. The study found similar uptake in both patients and controls, indicating limited diagnostic value.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

GASTRIC MOTILITY HYPOTESIS.

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2018
Same author

[Duodenal motility in norm and in some diseases. Hypothesis].

Terapevticheskii arkhiv·2016
Same author

The results of first rib resection in thoracic outlet syndrome.

Orthopedics·2014
Same author

[Pathological physiology of gastroesophageal reflux disease. Hypothesis (Literature review)].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology·2014
Same author

Is there visceral adipose tissue (VAT) intracellular hypercortisolism in human obesity?

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2013
Same author

Post-traumatic syndrome.

Journal of the Royal Society of Medicine·2010

Area of Science:

  • Nuclear medicine
  • Diagnostic imaging
  • Musculoskeletal disorders

Background:

  • Chest pain is a common presenting complaint in emergency departments.
  • Costochondritis is a frequent cause of non-cardiac chest pain.
  • Accurate diagnosis of costochondritis is essential to avoid unnecessary cardiac investigations.

Purpose of the Study:

  • To evaluate the specificity of bone imaging with 99mTc methylene diphosphonate for diagnosing costochondritis.
  • To determine if technetium uptake patterns can differentiate costochondritis from other causes of chest pain.

Main Methods:

  • A prospective, nonblinded, controlled study involving 20 patients with clinically diagnosed costochondritis and 10 control subjects.
  • Bone imaging was performed using intravenous 99mTc methylene diphosphonate.

Related Experiment Videos

  • Scans were independently reviewed by two nuclear medicine specialists.

    • Main Results:

    • 16 out of 20 patients with costochondritis showed increased technetium uptake at costochondral junctions.
    • Six patients also had increased uptake in other chest wall areas.
    • All 10 control subjects demonstrated increased technetium uptake at costochondral junctions.

    Conclusions:

    • Bone imaging with 99mTc methylene diphosphonate lacks specificity for diagnosing costochondritis.
    • The imaging technique showed similar uptake patterns in both patients with costochondritis and healthy controls.
    • This suggests bone scintigraphy is not a reliable method for confirming costochondritis in patients presenting with chest pain.