Related Experiment Videos
Rescuing corrupted gel files from Model 377 and 373 DNA Sequencers
K M O'Brien1, J W Fondon, G A Evans
1Eugene McDermott Center for Human Growth and Development, University of Texas, Southwestern Medical Center, Dallas 75235-8591, USA.
Biotechniques
|June 1, 1997
Summary
Automated DNA sequencing generates vast data. A new software solution leverages Macintosh computer architecture to prevent data loss from computer failures, safeguarding sequencing experiments.
Area of Science:
- Genomics and Bioinformatics
- Computer Science Applications in Biology
Background:
- Automated DNA sequencing generates substantial data volumes requiring significant computational resources.
- Computer failures during sequencing experiments can lead to irreversible loss of valuable data and experimental investment.
Purpose of the Study:
- To develop a method for preventing data loss in automated DNA sequencing due to computer failure.
- To utilize the data storage architecture of Macintosh computers for enhanced data security in sequencing.
Main Methods:
- The study involved analyzing the data storage architecture of Macintosh computers.
- Software was developed to integrate this architecture with automatic sequencers from PE Applied Biosystems.
Main Results:
- A software solution has been successfully developed.
- This software enables the prevention of data loss from computer failures in automated DNA sequencing.
Conclusions:
- The developed software effectively safeguards sequencing data by utilizing Macintosh computer architecture.
- This solution offers a free and accessible method to prevent data loss, preserving experimental investments.