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Related Experiment Videos

Pertussis notifications in Australia, 1991 to 1997

R Andrews1, A Herceg, C Roberts

  • 1National Centre for Epidemiology and Population Health, Australian National University, Canberra.

Communicable Diseases Intelligence
|May 29, 1997
PubMed
Summary

Pertussis remains epidemic in Australia despite high vaccination rates, particularly affecting infants and school children. The study suggests current whole-cell pertussis vaccines may offer short-term immunity, necessitating improved surveillance and vaccination strategies.

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Area of Science:

  • Public Health
  • Epidemiology
  • Vaccinology

Background:

  • Pertussis (whooping cough) is a vaccine-preventable disease.
  • Australia has experienced pertussis epidemics since 1993, with recent infant fatalities.
  • Despite high primary vaccination coverage (~90%), pertussis remains a significant public health concern.

Purpose of the Study:

  • To analyze national pertussis notification trends in Australia from 1991 to 1997.
  • To identify high-risk age groups for pertussis.
  • To evaluate the potential impact of vaccination strategies and identify surveillance gaps.

Main Methods:

  • Review of national pertussis notifications data from 1991 to 1997.
  • Analysis of notification rates by population and age group.

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  • Examination of trends in relation to vaccination coverage and booster introduction.
  • Main Results:

    • Pertussis notification rates peaked in 1994 (30.5/100,000) despite high primary vaccination coverage.
    • Infants (<1 year) and school-aged children (5-14 years) had the highest notification rates.
    • A decrease in age-specific rates for children aged 1-7 years was observed following the DTP booster introduction, suggesting potential efficacy.

    Conclusions:

    • The current whole-cell pertussis vaccine may provide only short-term immunity.
    • Low or inadequate vaccine coverage in the general population and among cases might contribute to ongoing epidemics.
    • Significant gaps exist in national surveillance, including under-reporting and lack of detailed vaccination status data for notified cases.