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Updated: Aug 17, 2026
07:42
An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
The significance of candiduria
The Tohoku Journal of Experimental Medicine
|May 1, 1977
Abstract:
Candida, which is not detectable in the urine of healthy individuals, was found in 6.5% of patient's urine. Most of the patients developing candiduria had higher-titered circulating antibody to the fungus than healthy persons did. There existed a definite relationship between the serum antibody titer and the duration of candiduria. These two variables reflected the status of the patient.
Insights
Candida in urine (candiduria) was detected in 6.5% of patients, unlike healthy individuals. Higher antibody titers in patients correlated with candiduria duration, indicating its significance in reflecting patient status.
Area of Science:
- Medical Mycology
- Clinical Microbiology
- Immunology
Background:
- Candida is a fungus not normally found in urine.
- Candiduria, the presence of Candida in urine, can indicate infection.
Purpose of the Study:
- To investigate the prevalence of candiduria in patients.
- To explore the relationship between serum antibody titers and candiduria.
- To assess the utility of these markers in reflecting patient status.
Main Methods:
- Urine samples were analyzed for the presence of Candida.
- Serum antibody titers against Candida were measured in patients and healthy controls.
- Correlation analysis was performed between antibody titers and candiduria duration.
Main Results:
- Candida was detected in the urine of 6.5% of patients.
- Patients with candiduria exhibited higher serum antibody titers compared to healthy individuals.
- A significant correlation was observed between serum antibody titer and the duration of candiduria.
Conclusions:
- Candiduria occurs in a subset of patients and is associated with an elevated immune response.
- Serum antibody titers and candiduria duration are valuable indicators of a patient's condition.
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