Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Tramadol in acute pain]

K A Lehmann1

  • 1Service d'Anesthésie et de Réanimation Chirurgicale, Université de Cologne, Allemagne.

Drugs
|January 1, 1997
PubMed
Summary

Tramadol effectively manages moderate to severe postoperative pain with minimal cardiovascular and respiratory side effects. Its low abuse potential and synergistic opioid/non-opioid actions make it a preferred analgesic, though nausea is a common side effect.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The clinical picture of rheumatoid arthritis according to the 2010 American College of Rheumatology/European League Against Rheumatism criteria: is this still the same disease?

Arthritis and rheumatism·2011
Same author

[WHO recommendations for treatment of tumor pain. Development of an evaluation system].

Schmerz (Berlin, Germany)·2003
Same author

[Ketorolac and butylscopolamine in combination with alfentanil for renal lithotripsy].

Schmerz (Berlin, Germany)·2003
Same author

Transdermal fentanyl for the management of cancer pain: a survey of 1005 patients.

Palliative medicine·2002
Same author

[Pain, pain therapy, and the taking of blood samples by specialists. Open letter to a chamber of physicians].

Schmerz (Berlin, Germany)·2002
Same author

[Lack of pre-emptive analgesic effect of low-dose ketamine in postoperative patients. A prospective, randomised double-blind study].

Schmerz (Berlin, Germany)·2002

Area of Science:

  • Pharmacology
  • Pain Management

Context:

  • Tramadol has been used clinically since the late 1970s.
  • It is a centrally acting analgesic with weak opioid agonist properties.
  • Tramadol exhibits synergistic opioid and non-opioid mechanisms.

Purpose:

  • Review clinical experience with tramadol for acute postoperative pain.
  • Evaluate tramadol's efficacy and safety compared to other analgesics.
  • Assess tramadol's role in patient-controlled analgesia (PCA).

Summary:

  • Tramadol provides effective analgesia for postoperative pain via intramuscular and intravenous routes.
  • Equipotent doses show less respiratory and cardiac depression than morphine or pethidine.
  • Common adverse events include nausea and vomiting, manageable with prophylactic antiemetics.

Impact:

  • Tramadol is recommended for first-line management of postoperative pain.
  • It offers effective pain relief with a negligible abuse potential.
  • Combination therapy with NSAIDs can reduce tramadol dosage and adverse effects.

Related Experiment Videos