Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sarin poisoning on Tokyo subway

S Ohbu1, A Yamashina, N Takasu

  • 1Department of Internal Medicine, St. Luke's International Hospital, Tokyo, Japan.

Southern Medical Journal
|June 1, 1997
PubMed
Summary

This study details a mass casualty event where 641 victims presented with organophosphate poisoning symptoms. Critical patients experienced respiratory arrest and low cholinesterase, with delayed psychological effects observed post-recovery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The reliability of computed tomography (CT) values and dimensional measurements of the oropharyngeal region using cone beam CT: comparison with multidetector CT.

Dento maxillo facial radiology·2008
Same author

Link between obstructive sleep apnea and increased bone resorption in men.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2008
Same author

[Preoperative antifungal agent for pulmonary aspergilloma].

Kyobu geka. The Japanese journal of thoracic surgery·2006
Same author

Cardioprotective effect of edaravone against ischaemia-reperfusion injury in the rabbit heart before, during and after reperfusion treatment.

The Journal of international medical research·2006
Same author

[Castleman disease in the posterior mediastinum showing atypical feature in computed tomography; report of a case].

Kyobu geka. The Japanese journal of thoracic surgery·2005
Same author

[Coronary artery dissection following angioplasty evaluated by fractional flow reserve: report of three cases].

Journal of cardiology·2002

Area of Science:

  • Toxicology
  • Emergency Medicine
  • Environmental Health

Background:

  • A mass casualty incident occurred, leading to a significant influx of patients at St. Luke's International Hospital.
  • Victims presented with a range of symptoms indicative of exposure to a toxic agent, necessitating immediate medical evaluation and management.

Purpose of the Study:

  • To document the clinical presentation, management, and outcomes of victims exposed during a mass casualty event.
  • To identify key signs and symptoms associated with the exposure, including critical indicators and common manifestations.
  • To assess the short-term and long-term health consequences, including physical and psychological effects, and secondary contamination.

Main Methods:

  • Retrospective review of 641 victims presenting to St. Luke's International Hospital following a disaster.

Related Experiment Videos

  • Clinical assessment of vital signs, neurological status, and laboratory values (serum cholinesterase) in critical patients.
  • Documentation of presenting signs and symptoms, treatment interventions, and patient outcomes, including follow-up for persistent effects.

    • Main Results:

    • Five critical patients presented with cardiopulmonary arrest, miosis, and low serum cholinesterase; two died, three recovered.
    • 106 patients were hospitalized with mild to moderate exposure symptoms, including pregnant women; others had transient symptoms.
    • Common symptoms included miosis, headache, dyspnea, nausea, and visual disturbances; psychological sequelae like PTSD were noted.
    • Secondary contamination affected over 20% of healthcare staff, indicating the need for stringent decontamination protocols.

    Conclusions:

    • Organophosphate poisoning can lead to severe acute toxicity, including respiratory arrest, and requires prompt medical intervention.
    • While physical symptoms may resolve, significant psychological impacts such as PTSD can persist, necessitating long-term care.
    • Effective management of mass casualty events involving toxic exposures requires robust emergency response and awareness of secondary contamination risks.