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Growth hormone, osteoblasts, and marrow adipocytes: a case report
H Kröger1, E Soppi, N Loveridge
1Department of Surgery, Kuopio University Hospital, FIN-70210 Kuopio, Finland.
Calcified Tissue International
|July 1, 1997
Summary
Growth hormone treatment increased osteoblast numbers and bone formation markers in vivo. This suggests growth hormone may direct precursor cells towards bone formation rather than fat storage.
Area of Science:
- Endocrinology
- Bone Biology
- Osteoporosis Research
Background:
- Growth hormone (GH) is known to stimulate bone formation markers in adults.
- However, its direct in vivo effects on osteoblasts, the bone-building cells, remained unclear.