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Course and prognosis in patients > or = 70 years of age with congestive heart failure and normal versus abnormal left

R Pernenkil1, J M Vinson, A S Shah

  • 1Division of Cardiology, Barnes-Jewish Hospital at Washington University Medical Center, St. Louis, Missouri 63110, USA.

Insights

Many older adults hospitalized for heart failure have normal heart pumping function. Reduced ejection fraction predicts worse outcomes at 3 months, but not long-term survival in elderly heart failure patients.

Area of Science:

  • Cardiology
  • Geriatric Medicine
  • Heart Failure Research

Background:

  • Congestive heart failure (CHF) is a common condition in elderly patients.
  • Left ventricular systolic function and ejection fraction are key indicators of heart health.
  • The prognostic value of preserved ejection fraction in geriatric CHF populations requires further investigation.

Purpose of the Study:

  • To investigate the prevalence of normal left ventricular systolic function in hospitalized elderly patients with CHF.
  • To determine the prognostic significance of reduced left ventricular ejection fraction in this population at short-term (3 months) and long-term (1 year) follow-up.

Main Methods:

  • Retrospective analysis of 501 patients aged 70 years or older admitted for CHF.
  • Assessment of left ventricular systolic function and ejection fraction.
  • Evaluation of adverse prognosis at 3 months and 1 year post-discharge.

Main Results:

  • 34.1% of elderly CHF patients exhibited normal left ventricular systolic function.
  • Reduced left ventricular ejection fraction was identified as an independent predictor of adverse prognosis at 3 months.
  • This association between reduced ejection fraction and adverse prognosis was not significant at 1 year.

Conclusions:

  • A substantial proportion of elderly patients hospitalized with CHF have preserved systolic function.
  • Left ventricular ejection fraction is a valuable short-term prognostic marker in this demographic.
  • The prognostic impact of ejection fraction diminishes over longer follow-up periods in elderly CHF patients.

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