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Multicentric eighth cranial nerve schwannoma

D Li1, U Fisch

  • 1Department of Otolaryngology-Head and Neck Surgery, University Hospital, Zurich, Switzerland.

Archives of Otolaryngology--Head & Neck Surgery
|June 1, 1997
PubMed
Summary

This study reports a rare case of multicentric eighth cranial nerve schwannoma, detailing its diagnosis and surgical management. The findings highlight the need for further research into the genetic and clinical aspects of this uncommon condition.

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Area of Science:

  • Neuro-oncology
  • Otolaryngology
  • Neurosurgery

Background:

  • Multicentric eighth cranial nerve schwannoma is exceedingly rare, with only three histopathologically confirmed cases reported since 1981.
  • Eighth cranial nerve schwannomas, also known as vestibular schwannomas, typically arise as solitary tumors.

Observation:

  • A patient presented with two distinct, isolated eighth cranial nerve schwannomas originating from the left cochlea and the left internal auditory canal.
  • Magnetic resonance imaging (MRI) was crucial for preoperative diagnosis, with intraoperative findings and histopathology confirming the presence of two separate tumors.

Findings:

  • The case represents a rare instance of multicentricity in eighth cranial nerve schwannoma.
  • Histopathological analysis confirmed the diagnosis of schwannoma for both isolated lesions.

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  • The transotic surgical approach was successfully employed for complete tumor resection.

    • Implications:

    • This case underscores the importance of considering multicentricity in the differential diagnosis of eighth cranial nerve tumors.
    • Further investigation into the genetic and molecular underpinnings of multicentric eighth cranial nerve schwannoma is warranted.
    • The transotic approach is highlighted as an effective surgical strategy for managing such complex cases.