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Radiation-induced brachial plexopathy: MR imaging

H Wouter van Es1, A M Engelen, T D Witkamp

  • 1Department of Radiology, University Hospital Utrecht, The Netherlands.

Skeletal Radiology
|May 1, 1997
PubMed
Summary
This summary is machine-generated.

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Magnetic resonance (MR) imaging reveals varied appearances of radiation-induced brachial plexopathy. Radiation fibrosis can present as low or high signal intensity on T2-weighted images and enhance even decades after therapy.

Area of Science:

  • Radiology
  • Neurology
  • Oncology

Background:

  • Radiation therapy for cancers like breast carcinoma and Hodgkin's lymphoma can affect the brachial plexus.
  • Radiation-induced brachial plexopathy presents with symptoms in the arm and hand, necessitating differentiation from tumor recurrence.

Observation:

  • MR imaging was utilized to evaluate three patients with clinical suspicion of radiation-induced brachial plexopathy.
  • Two patients had breast carcinoma and one had Hodgkin's lymphoma, all receiving radiation to the axilla and supraclavicular region.

Findings:

  • MR imaging demonstrated diverse appearances of radiation fibrosis.
  • Fibrosis showed low signal intensity in one patient and high signal intensity in two patients on T2-weighted images.
  • Gadolinium enhancement of fibrosis was observed in one patient 21 years post-radiation therapy.

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Implications:

  • Radiation-induced brachial plexopathy exhibits variable MR imaging characteristics.
  • Understanding these varied appearances is crucial for accurate diagnosis and management.
  • MR imaging findings, including signal intensity and enhancement patterns, can persist long after radiation treatment.