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Misdiagnosis of cancer due to multiple glove powder granulomas
1Department of Surgical Oncology, Norwegian Radium Hospital, University of Oslo, Norway.
Abstract:
A biologically absorbable powder, the cornstarch lubricant used in the production of gloves, is treated with epichlorohydrin, a cross-linking agent forming one to three diether glycerine groups to create a glove lubricating powder. This agent, together with chemicals used in glove fabrication is able to interfere with important biological diagnostic procedures, such as polymerase chain reaction (PCR) and enzyme immunoassay as well as to induce a granulomatous reaction in traumatised surgical tissue.