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Related Experiment Videos

Multi-purpose mechanical circulatory device

T V Mussivand1, P J Hendry, R G Masters

  • 1Cardiovascular Devices Division, University of Ottawa Heart Institute, Ontario, Canada.

The International Journal of Artificial Organs
|April 1, 1997
PubMed
Summary
This summary is machine-generated.

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A novel totally implantable mechanical circulatory assist device offers long-term ventricular support without percutaneous connections. Early in vitro and in vivo tests show its effectiveness for heart failure patients.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Implantable Technology

Background:

  • Mechanical circulatory assist devices (MCADs) are crucial for managing advanced heart failure.
  • Current MCADs often require percutaneous connections, increasing infection risk and limiting patient mobility.
  • Development of totally implantable systems is essential for improving long-term patient outcomes and quality of life.

Purpose of the Study:

  • To develop and evaluate a totally implantable mechanical circulatory assist device for long-term use.
  • To assess the feasibility of transcutaneous energy and information transfer for powering and controlling the device.
  • To explore applications for left, right, or bi-ventricular support and total artificial hearts.

Main Methods:

  • In vitro durability testing for 1-4 years.

Related Experiment Videos

  • In vivo experiments in bovine models for up to 96 hours of sustained circulation.
  • Utilized transcutaneous energy and information transfer sub-systems for wireless power and control.

    • Main Results:

    • The system demonstrated effective function as a totally implantable ventricular assist device in both in vitro and in vivo evaluations.
    • Transcutaneous systems enabled wireless powering, monitoring, and control, eliminating percutaneous connections.
    • Durability testing confirmed device resilience for extended periods.

    Conclusions:

    • The developed totally implantable ventricular assist device shows significant promise for long-term cardiac support.
    • Transcutaneous energy and information transfer effectively addresses the limitations of percutaneous connections.
    • Further chronic in vivo evaluation and design optimization are warranted for clinical translation.