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Updated: Aug 6, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Tissue expansion prior to revision total knee arthroplasty
R F Santore1, D Kaufman, A J Robbins
1Department of Orthopaedic Surgery, University of California San Diego, USA.
Abstract:
The first case of the use of a tissue expander in revision total knee surgery is reported. A 76-year-old woman presented with extremely adherent scare tissue on the anterior proximal tibia that was the result of multiple debridements and skin grafting for an infected primary total knee arthroplasty. The tissue expander was placed prior to subsequent revision total knee arthroplasty to permit complete excision of the scar and to provide tension-free closure with normal skin at the time of revision. Three years after the surgery, the patient is doing well.

