Central nervous system ischemia after varicella infection and desmopressin therapy for enuresis
J M Wieting1, D D Dykstra, M P Ruggiero
1Department of Physical Medicine and Rehabilitation, Michigan State University, College of Osteopathic Medicine, East Lansing 48824, USA.
Abstract:
A 7-year-old boy had a left-sided cerebrovascular accident 48 hours after beginning intranasal desmopressin acetate (DDAVP) therapy for persistent secondary nocturnal enuresis and approximately 2 weeks after varicella infection. A possible connection between desmopressin therapy or varicella infection (or both) and the patients neurologic symptoms is discussed, as is the relationship of desmopressin with hypercoagulability, Suggestions for patient/parent education, medical history taking, and patient surveillance are offered to prescribing physicians.
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