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Malignant chondroid syringoma presenting as multiple pulmonary nodules
1Department of Respiratory Medicine, St Vincent's Hospital, Dublin, Ireland.
Thorax
|April 1, 1997
Summary
Malignant chondroid syringoma, a rare skin tumor, metastasized to the lungs in a 50-year-old woman. A 17-year-old skin biopsy confirmed the pulmonary lesions as metastases, aiding diagnosis.
Area of Science:
- Oncology
- Dermatopathology
- Pulmonary Medicine
Background:
- Malignant chondroid syringoma is an exceedingly rare skin adnexal tumor.
- Pulmonary metastases from cutaneous adnexal tumors are exceptionally uncommon.
Observation:
- A 50-year-old woman presented with multiple pulmonary nodules.
- Initial diagnosis was challenging due to histopathological resemblance to pulmonary hamartoma.
- A 17-year-old skin biopsy of a hand lesion was crucial for definitive diagnosis.
Findings:
- The pulmonary lesions were definitively identified as metastases from a primary malignant chondroid syringoma.
- The tumor exhibited indolent behavior, with metastases appearing after a significant latency period.
Implications:
- This case highlights the importance of thorough patient history and prior biopsy review in diagnosing rare metastatic tumors.
- It underscores the potential for indolent cutaneous adnexal tumors to metastasize, even after many years.
- Accurate histopathological evaluation is critical for differentiating metastatic disease from primary lung tumors.