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Acute myelogenous leukaemia in a mare
1Department of Large Animal Clinical Sciences, University of Florida, Gainesville 32610, USA.
Australian Veterinary Journal
|May 1, 1997
Summary
A 5-year-old Thoroughbred mare was diagnosed with acute myelogenous leukemia, a rare cancer in horses, presenting with weight loss and fever. Despite treatment, the mare
Area of Science:
- Equine medicine
- Veterinary oncology
- Hematology
Background:
- Acute myelogenous leukemia (AML) is a rare and aggressive cancer affecting blood cell development.
- Diagnosis in horses often presents challenges due to non-specific clinical signs.
Observation:
- A 5-year-old Thoroughbred mare exhibited weight loss, fever, and leukopenia over four weeks.
- Physical examination revealed a palpable abdominal mass, enlarged spleen, and a large fetus.
- Hematological findings included anemia, thrombocytopenia, and hyperfibrinogenemia.
Findings:
- Bone marrow cytology and cytochemical staining confirmed acute myelogenous leukemia.
- The mare's condition rapidly deteriorated despite medical interventions.
Implications:
- This case highlights the importance of considering hematological malignancies in horses with persistent fever and weight loss.
- Early diagnosis and understanding of AML in horses are crucial for potential therapeutic strategies.
- Further research into equine leukemia is warranted to improve diagnostic and treatment outcomes.