Ribozymes: red in tooth and claw
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1Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.
Current Biology : CB
|June 1, 1997
Abstract:
A population of catalytic RNA molecules has been engineered to operate and evolve in vitro in a continuous manner. The novel continuity of the process allows the propagation of many generations in a very short time and without the manual manipulation necessary with traditional in vitro selection techniques.