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Updated: Aug 14, 2026

One-step Negative Chromatographic Purification of Helicobacter pylori Neutrophil-activating Protein Overexpressed in Escherichia coli in Batch Mode
Published on: June 18, 2016
New developments in Helicobacter pylori eradication therapy
1University Dept. of Medicine, Royal Free Hospital School of Medicine, London, UK.
Background:
The optimal strategy for the eradication of Helicobacter pylori has yet to be determined. This paper summarizes some of the latest treatment strategies for eradicating H. pylori infection.
Method:
Literature review by author.
Results:
Successful eradication of H. pylori requires the use of combination therapy involving control of gastric acid secretion together with anti-microbial drugs. The two most popular strategies use either a proton-pump inhibitor or an H2 antagonist plus two antibiotics-usually metronidazole, amoxycillin or clarithromycin. Ranitidine bismuth citrate is a co-precipitate of ranitidine hydrochloride and bismuth citrate, producing a high rate of H. pylori eradication when combined with clarithromycin. Future development of this combination may involve the addition of a second antibiotic.
Conclusion:
Modern combination therapy usually results in an 80-95% H. pylori eradication rate in compliant patients.
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