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Updated: Aug 1, 2026
CRISPR-mediated Genome Editing of the Human Fungal Pathogen Candida albicans
Published on: November 14, 2018
Molecular cloning of a Candida albicans gene (SSB1) coding for a protein related to the Hsp70 family
V Maneu1, A M Cervera, J P Martinez
1Department de Microbiología y Ecología, Facultad de Farmacia, Universitat de València, Spain.
Abstract:
We have cloned and sequenced a Candida albicans gene (SSB1) encoding a potential member of the heat-shock protein seventy (hsp70) family. The protein encoded by this gene contains 613 amino acids and shows a high degree (85%) of sequence identity to the ssb subfamily (ssb1 and ssb2) of the Saccharomyces cerevisiae hsp70 family. The transcribed mRNA (2.1 kb) is present in similar amounts both in yeast and germ tube cells of C. albicans.
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