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[V gene repertoire and pathogenic autoantibodies]
Y Hirabayashi1, Y Munakata, S Saitou
1Department of Internal Medicine, Tohoku University School of Medicine.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|June 1, 1997
Summary
No specific V genes identify pathogenic autoantibodies in humans. However, certain V genes are preferentially used, and B cell development may be dysregulated in autoimmune diseases like SLE.
Area of Science:
- Immunology
- Genetics
- Autoimmunity