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Simvastatin-induced myopathy in a patient treated for hypercholesterolemia. Morphological aspects
E Wicher-Muniak1, K Zmudka, W Dabroś
1Department of Clinical and Experimental Pathomorphology, Jagiellonian University Medical College, Kraków.
Abstract:
Functional and histological changes in skeletal muscle developing during hypolipemic therapy, especially with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors are rare. This paper reports a case of simvastatin-induced myopathy confirmed histopathologically and ultrastructurally.