Related Experiment Videos
Multifocal osteosarcoma in a patient with Fanconi anemia
1Oregon Health Sciences University, Portland, USA.
Purpose:
The purpose of this report is to present a case of multifocal osteosarcoma in a patient with Fanconi anemia.
Patients And Methods:
A nine year old girl with known Fanconi anemia presented with a pathologic femur fracture. Imaging studies confirmed soft tissue and bony involvement in the femur, ipsilateral tibia, and possibly contralateral femur.
Results:
Biopsy and subsequent amputation confirmed the presence of classic osteosarcoma in the involved femur and ipsilateral tibia. The patient died seven months later of pulmonary failure secondary to metastases.
Conclusion:
Fanconi anemia is known to be associated with malignancies such as leukemias. We report a new association of Fanconi anemia with osteosarcoma.