Twenty psychotic males with Klinefelter's syndrome

Twenty males with Klinefelter's syndrome discharged from psychiatric hospitals with diagnoses classified as psychosis are presented. It is concluded that the higher frequency of psychoses in males with the Klinefelter syndrome most probably is due to reactive psychosis. Personality traits commonly found in these males may explain this. The importance of early diagnosis of the Klinefelter syndrome is stressed, as it is believed that treatment and advice in due time may prevent most of the reactive psychoses.