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Comparison of early target organ damage between blacks and whites with mild systemic arterial hypertension
R E Schmieder1, J K Rockstroh, G Lüchters
1Department of Medicine IV, University of Erlangen-Nuremberg, Germany.
Insights
Race does not appear to affect early target organ damage in arterial hypertension. A matched-pair analysis found no racial disparities in organ damage markers between Black and White hypertensive patients with similar blood pressure levels.
Area of Science:
- Cardiovascular Medicine
- Hypertension Research
- Racial Health Disparities
Background:
- Arterial hypertension is linked to increased mortality and morbidity.
- Previous reports suggest higher rates of target organ damage in Black hypertensives compared to White hypertensives.
Purpose of the Study:
- To investigate if race itself influences early target organ damage in arterial hypertension.
- To compare organ damage markers between Black and White hypertensive individuals at similar blood pressure levels.
Main Methods:
- A matched-pair analysis was conducted.
- Confounding factors including age, sex, weight, and arterial pressure were controlled.
Main Results:
- No significant racial disparities were observed in markers of early target organ damage.
- The findings held true for matched Black and White hypertensive patients with similar blood pressure.
Conclusions:
- Race per se does not appear to be an independent risk factor for early target organ damage in arterial hypertension.
- After adjusting for key variables, racial differences in organ damage markers are not detected.
Abstract:
As greater mortality and morbidity from target organ damage in arterial hypertension have been reported for black than for white hypertensives, we examined in a matched-pair analysis whether race per se affected markers of early target organ damage at similar levels of blood pressure. After controlling for the confounding factors such as age, sex, weight, and arterial pressure that interact with hypertension-related target organ damage, no racial disparities could be detected between matched black and white hypertensive patients.