Abnormal duodenal loop and pyloric regurgitation

In a series of 48 patients with dyspepsia but without gastric ulcer it is shown that pyloric regurgitation occurred significantly more often in patients with distal and combined anomalies of the duodenum or a short loop than in patients with a normal duodenal loop. No difference existed between patients with proximal duodenal anomalies and the normal group. When pyloric regurgitation occurred in the erect position it could be prevented in the supine position and also to some extent by intravenous by intravenous administration of 20 mg metochlopramide.