Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Side effects associated with pneumococcal vaccination

K L Nichol1, R MacDonald, M Hauge

  • 1Medical Service, VA Medical Center, Minneapolis, MN 55417, USA.

American Journal of Infection Control
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multidisciplinary study of thorium mobility: formation of turkestanite and steacyite analogues, and structural insights using an XRD-directed microcrystal preparation technique.

Acta crystallographica Section B, Structural science, crystal engineering and materials·2025
Same author

Alzheimer's disease and its treatment-yesterday, today, and tomorrow.

Frontiers in pharmacology·2024
Same author

Flow cytometer for a dilution-free measurement approach with sample recollection.

The Review of scientific instruments·2024
Same author

Camera-based CW Diffuse Optical Tomography for obtaining 3D absorption maps by means of digital tomosynthesis.

Biomedical physics & engineering express·2022
Same author

Monitoring intrapartum fetal heart rates by mothers in labour in two public hospitals: an initiative to improve maternal and neonatal healthcare in Liberia.

BMC pregnancy and childbirth·2020
Same author

Survival of women with early-stage cervical cancer in the UK treated with minimal access and open surgery.

BJOG : an international journal of obstetrics and gynaecology·2019

Pneumococcal vaccination is safe for older adults, with no increase in systemic side effects. Mild local reactions occurred in about a quarter of recipients, addressing a key barrier to immunization.

Area of Science:

  • Immunology
  • Public Health
  • Vaccinology

Background:

  • Pneumococcal disease poses a significant health risk, particularly for the elderly and high-risk populations.
  • Despite recommendations, pneumococcal vaccination rates remain low, with underuse attributed to concerns about side effects.
  • Addressing vaccine hesitancy is crucial for improving public health outcomes.

Purpose of the Study:

  • To evaluate the safety of pneumococcal vaccination by assessing systemic and local side effects.
  • To provide data that can help overcome barriers to pneumococcal immunization.

Main Methods:

  • A survey of 1006 individuals attending a vaccination clinic was conducted.
  • Participants were interviewed about their health and experienced symptoms during the week after vaccination.

Related Experiment Videos

  • Reported symptoms were compared to a baseline period prior to vaccination.

    • Main Results:

    • No increase in systemic symptoms (fever, rash, myalgias, fatigue, malaise, headache) was observed post-vaccination.
    • Local reactions, such as injection site discomfort, occurred in 28.2% of recipients.
    • Over 90% of local reactions were mild to moderate and did not significantly impair arm use.

    Conclusions:

    • Pneumococcal vaccination is not associated with an increase in systemic symptoms.
    • Mild to moderate local symptoms are common in a subset of vaccine recipients.
    • These findings can help alleviate patient concerns and improve vaccination uptake.