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Hyperimmunoglobulinemia D in idiopathic retinal vasculitis
Y Kumano1, T Nagato, K Kurihara
1Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Summary
Elevated immunoglobulin D (IgD) levels were found in patients with Behçet's disease and idiopathic retinal vasculitis. This suggests a potential new clinical entity linked to abnormal B cell activity and immune responses.
Area of Science:
- Ophthalmology
- Immunology
- Rheumatology
Background:
- Idiopathic retinal vasculitis and Behçet's disease are associated with elevated serum immunoglobulin D (IgD) levels.
- Investigated clinical features and the relationship between retinal vasculitis and serum IgD in uveitis patients.
- Four patients with idiopathic retinal vasculitis and elevated serum IgD were examined.