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Distribution of intraperitoneal chemotherapy into the pleural cavity
L Vaccarello1, V Berghella, S C Rubin
1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Background:
Intraperitoneal chemotherapy is an established treatment for abdominal and pelvic malignancies. Several catheter-related complications have been reported. We report a case of abnormal distribution of intraperitoneal chemotherapy into the pleural cavity.
Case:
A patient receiving intraperitoneal cisplatin developed shortness of breath. A pleural effusion was diagnosed and was evacuated by thoracentesis. Abnormal distribution of instilled fluid was responsible for her distress.
Conclusion:
Communications exist between the peritoneal and pleural cavities. The use of intraperitoneal chemotherapy or radioactive material may lead to respiratory complications if abnormal distribution occurs.