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[Early changes in cardiac function and beta-ARs in heart after severe scalds in rat]
Abstract:
The changes in left ventricular function and ventricle beta-adrenoceptors (beta-ARs) were measured in rat undergoing a full thickness scalded burn of skin of 30% total body surface area. The results showed that there were a significant decrease in left ventricular systolic pressure (LVSP), maximum rising and falling rate of left intraventricular pressure (LV +/- dp/dtmax) and density of ventricular beta-ARs. Correlation analysis showed that the change in beta-ARs density correlated with the change in LVSP, LV +/- dp/dtmax positively.