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[Mycethemia: an analysis of 56 cases]
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi = Zhonghua Zheng Xing Shao Shang Waikf [I.E. Waike] Zazhi = Chinese Journal of Plastic Surgery and Burns
|March 1, 1996
Summary
Fungal infections in burn patients, particularly Candida albicans, show a significant increase in incidence and decrease in mortality after 1985. This highlights evolving treatment efficacy for mycethemia in burn care.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Burn Patient Care
Context:
- Mycethemia (fungal infection) is a serious complication in burn patients.
- Historical data from 1958-1992 provides a long-term perspective on fungal infections in this vulnerable population.
- Candida albicans was identified as the predominant fungal pathogen.
Purpose:
- To analyze the incidence and mortality rates of mycethemia in burn patients over a 35-year period.
- To identify trends in fungal infections, specifically comparing pre- and post-1985 data.
- To investigate the clinical characteristics, causes, diagnosis, and treatment of mycethemia in burn patients.
Summary:
- A retrospective study of 56 burn patients diagnosed with mycethemia between 1958 and 1992.
- Overall incidence was 0.39% with a 39.29% mortality rate.
- Significant changes observed post-1985: incidence rose to 0.58% (from 0.26%) and mortality decreased to 17.65% (from 72.73%), with Candida albicans being the most common pathogen (75% of cases).
Impact:
- Demonstrates a significant improvement in managing fungal infections in burn patients after 1985.
- Provides valuable insights for optimizing clinical strategies and reducing mortality associated with mycethemia in burn care.
- Highlights the importance of ongoing surveillance and adaptation of treatment protocols for fungal infections in immunocompromised patients.