Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Keratoconjunctivitis sicca in patients with lipoprotein (a) elevation]

R Wiedemann1, W Reuter, T Meier

  • 1Universitäts-Augenklinik Leipzig, Universität Leipzig.

Klinische Monatsblatter Fur Augenheilkunde
|January 1, 1997
PubMed
Summary

Elevated lipoprotein(a) [Lp(a)] levels are linked to dry eye disease (keratoconjunctivitis sicca). Over 80% of patients with high Lp(a) showed dry eye signs, though the Lp(a) level didn't correlate with severity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Techno-economic assessment at full scale of a biogas refinery plant receiving nitrogen rich feedstock and producing renewable energy and biobased fertilisers.

Journal of cleaner production·2021
Same author

Bright correlated twin-beam generation and radiation shaping in high-gain parametric down-conversion with anisotropy.

Optics express·2021
Same author

Motif lengths of circular codes in coding sequences.

Journal of theoretical biology·2021
Same author

Implementation and evaluation of a nurse-led decision-coaching program for healthy breast cancer susceptibility gene (BRCA1/2) mutation carriers: a study protocol for the randomized controlled EDCP-BRCA study.

Trials·2020
Same author

[Therapeutic alternatives to surgical treatment of malignant eyelid tumors and their precursors].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2020
Same author

[Treatment reality with ranibizumab in clinical routine use for patients with diabetic macular edema : 1‑year results of the German POLARIS cohort].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2018

Area of Science:

  • Ophthalmology
  • Cardiovascular Science
  • Genetics

Context:

  • Elevated lipoprotein(a) [Lp(a)] is a known risk factor for cardiovascular diseases.
  • Ophthalmologic manifestations associated with elevated Lp(a) are not well-documented.
  • This study investigates the potential link between high Lp(a) and dry eye disease.

Purpose:

  • To determine the incidence of keratoconjunctivitis sicca (dry eye) in patients with elevated Lp(a).
  • To assess the correlation between Lp(a) levels and the severity of dry eye signs.

Summary:

  • 27 patients with pathological Lp(a) levels underwent ophthalmologic examinations.
  • Results indicated significant signs of dry eye in over 80% of patients, with impression cytology being a sensitive diagnostic tool.

Related Experiment Videos

  • No correlation was found between Lp(a) levels and the degree of dry eye pathology.

    • Impact:

    • Suggests a potential association between elevated Lp(a) and dry eye disease.
    • Highlights the need for further research into the causal relationship.
    • May inform future screening and management strategies for patients with high Lp(a).