Office laparoscopy under local anesthesia for gamete intrafallopian transfer: technique and tolerance
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Updated: Nov 1, 2026

Embryo Transfer Surgery via Laparotomy in Gilts
Published on: October 18, 2024
1Department of Gynecology and Obstetrics, Stanford University School of Medicine, California 94305, USA.
Objective:
To describe our technique for laparoscopic GIFT under local anesthesia and to evaluate patient tolerance and surgeon satisfaction in 175 consecutive procedures.
Design:
Prospective cohort study.
Setting:
University infertility practice.
Patient(S):
All GIFT candidates from 1992 to 1996 were offered the procedure. Of 119 patients, 119 chose local anesthesia for 175 procedures and 1 patient elected to have general anesthesia.
Intervention(S):
Transvaginal ultrasound-guided egg retrieval followed by GIFT in the clinic procedure room with a 5-mm laparoscope and two accessory 3-mm trocars with local anesthesia and i.v. sedation.
Main Outcome Measure(S):
Patient tolerance and acceptance, duration of the procedure, amount of analgesics, surgeon satisfaction, and pregnancy rate (PR).
Result(S):
The laparoscopic portion lasted an average of 27 minutes, with a mean dose of 1.41 mg of midazolam and 68 micrograms of fentanyl used. Sixty-nine percent of the patients scored "very good," 20% "good," 9% "acceptable," and 2% "poor." All 38 patients undergoing 97 repeat procedures selected local anesthesia again. For women < 40 years of age, clinical PR and delivery rate were 43% and 38%, respectively.
Conclusion(S):
Routine office GIFT under local anesthesia is effective and well accepted by the surgeon and is preferred by patients. It offers a significant cost containment and scheduling flexibility in addition to high success rates.
