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Microbial growth inside saline-filled breast implants

V L Young1, M C Hertl, P R Murray

  • 1Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, Mo., USA.

Plastic and Reconstructive Surgery
|July 1, 1997
PubMed
Summary
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Saline in breast implants can support the growth of bacteria and fungi over time. Control implants showed no growth, but inoculated implants and surrounding tissues often did, indicating potential infection risks.

Area of Science:

  • Microbiology
  • Biomaterials Science
  • Infectious Diseases

Background:

  • Breast implant infections are a significant concern.
  • The role of intraluminal saline in supporting microbial growth is not fully understood.
  • Understanding microbial viability in implant materials is crucial for patient safety.

Purpose of the Study:

  • To investigate the potential for intraluminal saline in breast implants to support microbial growth.
  • To assess the survival and proliferation of common wound-infecting microorganisms in saline over extended periods.
  • To evaluate microbial contamination in both saline and surrounding capsular tissue in vivo.

Main Methods:

  • In vitro studies using sterile saline cultures with various bacteria and fungi.

Related Experiment Videos

  • In vivo study involving inoculation of breast implants in rabbits with test organisms.
  • Serial cultures of intraluminal saline and surrounding capsular tissue at 1, 3, and 6 months post-implantation.

    • Main Results:

    • In vitro: Klebsiella pneumoniae, Candida albicans, Aspergillus fumigatus, and Paecilomyces variotii survived in saline for 2 weeks.
    • In vivo: 7 of 10 inoculated organisms grew in intraluminal saline; none grew in control saline.
    • Capsular tissue cultures were positive in 17% of cases, often with organisms different from the inoculum.

    Conclusions:

    • Intraluminal saline in breast implants can support the growth of specific bacteria and fungi over prolonged periods.
    • Microbial contamination can occur within the implant and in the surrounding capsular tissue.
    • The findings highlight potential risks associated with microbial viability within breast implant materials.