Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Factitious hyperchloremia disclosing bromide poisoning. 4 cases]

B Bonnotte1, C Jolimoy, A Pacaud

  • 1Service de Médecine 1, Néphrologie et Endocrinologie, Chu, Dijon.

Presse Medicale (Paris, France : 1983)
|May 31, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of social cognition impairments in patients with amyotrophic lateral sclerosis: How can it be improved? A systematic review.

Revue neurologique·2025
Same author

Cyclophosphamide vs rituximab for eradicating inhibitors in acquired hemophilia A: A randomized trial in 108 patients.

Thrombosis research·2024
Same author

[What about the new ACR/EULAR classification criteria for giant cell arteritis?]

La Revue de medecine interne·2023
Same author

La Revue de medecine interne·2023
Same author

Mogamulizumab-induced granulomatous dermatitis of the scalp: a distinct entity associated with clinical response.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

[How to apply the EULAR and ACR recommendations for the diagnosis and treatment of giant cell arteritis?]

La Revue de medecine interne·2022

Elevated chloride levels may indicate bromism, a condition caused by bromide exposure. Discontinuing bromide-containing supplements can restore normal chloride levels and prevent neurological issues.

Area of Science:

  • Clinical Chemistry
  • Toxicology
  • Analytical Chemistry

Background:

  • Elevated chloride in routine blood tests can signal the presence of other halides like bromide.
  • Differentiating true hyperchloremia from halide interference is crucial for accurate diagnosis.

Observation:

  • Four patients presented with hyperchloremia and a decreased anion gap.
  • Long-term use of calcium bromogalacto-glucomate was identified as the source of bromide exposure.
  • Inductively coupled plasma mass spectrometry (ICP-MS) confirmed elevated blood bromide levels.

Findings:

  • Bromide accumulation led to pseudohyperchloremia.
  • Discontinuation of bromide-containing supplements normalized chloride levels.
  • Bromism can manifest with neurological, psychiatric, and dermatological symptoms.

Related Experiment Videos

Implications:

  • Bromism is an underdiagnosed condition that can mimic other electrolyte imbalances.
  • Awareness of bromide in certain medications and supplements is essential for clinicians.
  • Patient education regarding the risks of excessive bromide intake is critical to prevent adverse effects.