Related Experiment Video
Updated: Aug 12, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
Transmetatarsal amputation in the management of peripheral ischemia
Abstract:
It is often difficult to decide at what level to amputate the ischemic limb when reconstructive surgery has nothing further to offer. The trend has been towards amputation below the knee, but many surgeons are unwilling, in the presence of ischemia, to amputate at a lower level than this. In a series of sixty transmetatarsal amputations performed for ischemia, 70 percent healed. Absence of a popliteal pulse did not influence the outcome. The incidence of healing in diabetic and nondiabetic patients was similar. For a few carefully selected patients, transmetatarsal amputation may be a suitable and preferable alternative to below-knee amputation.
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management
Diabetic Foot Ulcer

