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Comparison of colloidal bismuth subcitrate and metronidazole, both in combination with an H2-antagonist as therapy
W Baffone1, F Belbusti, E Barbieri
1Institute of Toxicologic, Hygienic and Environmental Sciences, University of Urbino, Italy.
Abstract:
In this random study, the efficacy of either colloidal bismuth subcitrate (CBS) or metronidazole in combination with an H2-antagonist in the treatment of various gastric pathologies was evaluated, along with the trends in antibody levels. Among the 40 Helicobacter pylori-positive patients with various gastroduodenal pathologies who underwent chemotherapy, 27 were treated with CBS and 13 with metronidazole. H. pylori was eradicated in 48.14% of the patients treated with CBS and 53.8% of those treated with metronidazole. After therapy, no statistically significant or slight decrease in the serum levels of antibodies was found.