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Oculo-auriculo-vertebral spectrum: cranial and vertebral malformations due to focal disturbed chondrogenesis
M Goret-Nicaise1, G Baertz, P Saussoy
1Human Anatomy Research Unit, Faculty of Medicine, University of Louvain (UCL), Brussels, Belgium.
Journal of Craniofacial Genetics and Developmental Biology
|January 1, 1997
Abstract:
Microradiographic and histological analyses point out a focal disturbed chondrogenesis of both the skull base and the axial skeleton in a case of oculo-auriculo-vertebral spectrum. Cartilage showed disturbed endochondral ossification with defects in calcification, deficient resorption, and abnormal crumpled areas of mineralized cartilage.