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Portal vein thrombosis in association with factor V Leiden mutation in a patient with hepatocellular carcinoma
A Gürgey1, M Büyükpamukcu, C Baskut
1Department of Pediatrics, Hacettepe University, Ihsan Dogramaci Children Hospital, Ankara, Turkey.
Medical and Pediatric Oncology
|September 1, 1997
Abstract:
We report a case of hepatocellular carcinoma associated with portal vein thrombosis. Analysis of whole cellular DNA demonstrated heterozygosity for the factor V Leiden mutation. The patient also had marked protein C deficiency. The presence of the mutation associated with protein C deficiency may increase the risk of thrombosis in this patient with hepatocellular carcinoma.