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[Malignant hemangiopericytoma of the pelvis: treatment using internal hemipelvectomy]
O Heymans1, M Gebhart, D Larsimont
1Département de Chirurgie orthopédique, Institut J. Bordet, Bruxelles, Belgique.
Abstract:
Hemangiopericytoma is a rare vascular tumor originating from pericytes. The main manifestation is a growing mass. Although computed tomodensitometry and MRI are the best diagnostic procedures, the diagnosis is made only after microscopic examination. The malignancy of this tumor is not well established. In fact, there is a continuum between benign and malignant hemangiopericytoma. The malignancy is estimated by the number of mitoses and the cellularity. Recurrences occur in 60% of cases. The best treatment is surgical excision. The role of radiation therapy and chemotherapy is not well established. The history of a 51-year-old woman treated by internal hemipelvectomy is presented here.
Insights
Hemangiopericytoma, a rare pericyte tumor, presents as a growing mass. Diagnosis requires microscopy, and malignancy is graded by mitoses and cellularity, with a high recurrence rate necessitating surgical excision.
Area of Science:
- Oncology
- Pathology
- Vascular Biology
Background:
- Hemangiopericytoma is a rare vascular neoplasm arising from pericytes.
- Its primary clinical manifestation is a progressively enlarging mass.
- Diagnostic imaging like CT and MRI are valuable but definitive diagnosis relies on histopathology.
Observation:
- The distinction between benign and malignant hemangiopericytoma exists on a spectrum.
- Tumor malignancy is assessed based on mitotic activity and cellularity.
- Recurrence rates for hemangiopericytoma are reported in approximately 60% of cases.
Findings:
- Surgical excision is the primary treatment modality for hemangiopericytoma.
- The efficacy of adjuvant radiation therapy and chemotherapy remains uncertain.
- A case report details the treatment of a 51-year-old female patient with internal hemipelvectomy.
Implications:
- Further research is needed to establish clear diagnostic criteria for hemangiopericytoma malignancy.
- Optimal treatment strategies, including the role of non-surgical interventions, require further investigation.
- Understanding the behavior and management of hemangiopericytoma is crucial for improving patient outcomes.