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Antihyperglycemic activity of phenolics from Pterocarpus marsupium
M Manickam1, M Ramanathan, M A Jahromi
1Department of Medicinal Chemistry, Banaras Hindu University, Varanasi, India.
Journal of Natural Products
|June 1, 1997
Abstract:
Glucose levels in rats with hyperglycemia induced by streptozotocin were determined after i.p. administration of marsupsin (1), pterosupin (2), and pterostilbene (3), three important phenolic constituents of the heartwood of Pterocarpus marsupium. Marsupsin and pterostilbene significantly lowered the blood glucose level of hyperglycemic rats, and the effect was comparable to that of 1,1-dimethylbiguanide (metformin).