Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extended temporal bone resection for squamous cell carcinoma

D A Moffat1, P Grey, R H Ballagh

  • 1Department of Otoneurological and Skull Base Surgery, Addenbrooke's Hospital, Cambridge, United Kingdom.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgery of the lateral skull base: a 50-year endeavour.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2019
Same author

Factors affecting final facial nerve outcome following vestibular schwannoma surgery.

The Journal of laryngology and otology·2014
Same author

Nanocrystalline cellulose applied simultaneously as the gate dielectric and the substrate in flexible field effect transistors.

Nanotechnology·2014
Same author

Outcome of translabyrinthine surgery for vestibular schwannoma in neurofibromatosis type 2.

British journal of neurosurgery·2013
Same author

Reconstructive Middle Ear Surgery: Techniques to improve hearing.

Canadian family physician Medecin de famille canadien·2011
Same author

Immunoglobulin G4 related systemic sclerosing disease involving the temporal bone.

The Journal of laryngology and otology·2010
Same journal

Gender-Affirming Care in Otolaryngology: A State of the Art Review.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

Caffeine Consumption and Rhinologic Symptom Severity.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

Ethical Considerations in Using the Pernkopf Atlas in Otolaryngology Education Ethics in Practice: Point-Counterpoint.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

Preoperative Neutrophil-to-Lymphocyte Ratio Predicts Recurrence in HPV-Associated Oropharyngeal Cancer After Transoral Robotic Surgery.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

PEAK-II Trach: A Multi-Institutional Quality Improvement/Simulation Study Assessing Pediatric Emergency Readiness.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

Clinical Features, Treatment, and Outcomes for Oropharyngeal Adenoid Cystic Carcinoma: A Systematic Review.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
See all related articles

Extended temporal bone resection offers encouraging salvage outcomes for recurrent squamous cell carcinoma. This radical surgery shows promise for improving 5-year survival rates in advanced cases.

Area of Science:

  • Otolaryngology
  • Surgical Oncology
  • Head and Neck Cancer

Background:

  • Squamous cell carcinoma of the temporal bone presents treatment challenges, especially recurrent cases.
  • Conventional treatments like radiotherapy or partial resection yield low survival rates for advanced tumors.

Purpose of the Study:

  • To evaluate the surgical outcomes of extended temporal bone resection as a salvage procedure for recurrent squamous cell carcinoma.

Main Methods:

  • Retrospective analysis of 15 patients undergoing extended temporal bone resection.
  • Procedures included supraomohyoid neck dissection, dural grafting, and microvascular flap reconstruction.

Main Results:

  • Achieved a 47% 5-year survival rate.

Related Experiment Videos

  • Temporal lobe resection was necessary in 29% of survivors.
  • 13% had positive lymph nodes; all deaths occurred within the first year.
  • Tumor differentiation correlated with survival; poorly differentiated tumors were fatal.
  • Conclusions:

    • Extended temporal bone resection shows encouraging results for recurrent squamous cell carcinoma.
    • Radical surgery combined with radiotherapy may improve future survival compared to conventional methods.